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1910-11 — The CVM's first building, Connaway Hall, was built to house veterinary science faculty who taught agricultural students, investigated animal and poultry diseases, performed diagnostic and extension work, and produced animal vaccines.

1946 — The DVM curriculum was established. In 1950, 26 veterinarians were graduated in the first class. The CVM now enrolls 120 new students each year.

1965 — The Laboratory Animal Medicine training program (now the Comparative Medicine Program) was established.  This program has been partially funded by NIH (T32 and R25) since 1970 and has grown to be one of the largest and most respected post-DVM laboratory animal medicine training programs in the country.

1968 — The Research Animal Diagnostic Laboratory (RADIL) was established as an NIH-funded diagnostic and investigative laboratory. It was recently privatized.

— CVM researchers identified the protozoal organism Cytauxzoon felis, which causes Cytauxzoonosis, also known as bobcat fever, in domestic cats.

1983  — MU researchers began initial concept testing for TheraSphere in laboratory animals. The radioactive glass microspheres were later approved to combat liver cancer in people.

1985 — Initial concept testing for Samarium, a therapeutic agent to treat bone cancer, began in patient animals at the CVM. The Food and Drug Administration later approved use of the drug in human patients.

1993 —  Clydesdale Hall, the CVM’s $20 million facility built to house the Veterinary Medical Teaching Hospital, was dedicated.

2000 — The Mutant Mouse Regional Resource Center (MMRRC), one of four such centers funded by the NIH, was established.  This consortium of centers is the NIH's premier repository of spontaneous and induced mutant mouse models.  This national network of breeding and distribution facilities procures, distributes, and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines. 

2001 — The Rat Resource and Research Center (RRRC) was established in order to procure, distribute, and cryopreserve scientifically valuable, genetically engineered rat strains. It is the NIH's only repository of mutant rat models.
2003 — The National Swine Resource and Research Center (NSRRC) was established to serve as a central resource for reagents, creation of new genetically modified swine, and information and training related to use of swine models in biomedical research.

2005 — The Research Center for Human-Animal Interaction was established at MU. The collaboration between the CVM and Sinclair School of Nursing conducts studies and projects examining the benefits of human-animal interaction.

—  Dr. Kristina Narfstrom implanted light-sensing retinal microchips in the eyes of Abyssinian cats with a genetic disorder similar to retinitis pigmentosa in humans.

2007  —  After 20 years of research and gait analysis, Kevin Keegan, a professor of equine surgery at MU, made the Lameness Locator available to veterinarians. This device objectively detects and quantifies body movement asymmetry in a horse using small, wireless, body-mounted inertial sensors and a hand-held tablet PC.

2007 —  The CVM helped initiate a Master’s Degree in Public Health with an emphasis in veterinary medicine at MU.

2008 — The MU Comparative Neurology Lab, in partnership with investigators at the Broad Institute and Massachusetts Institute of Technology, established that the same genetic mutation that causes degenerative myelopathy (DM) in dogs also causes some forms of amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease in people. The team is now investigating therapies for DM and ALS as well as other neurological diseases, including Batten’s Disease.

2010 — An NIH-funded program that develops and refines Animal Models of Infectious Disease for a variety of pathogen-based NIAID/DMID projects and uses these models for in vivo screening and efficacy of therapeutics was established.

2010 — MU developed the Mizzou Advantage initiative to advance four key areas of strength. The CVM, a key partner in the One Health/One Medicine advantage, is leading collaborative research in animal and human health.

2010  — Veterinary medicine scientists began work within the MU Laboratory for Infectious Disease Research, a $16.5 million facility that is part of our nation’s biodefense effort.

2011 — The CVM began operations at a satellite radiation oncology facility in Wentzville, Mo. Mizzou Animal Cancer Care offers cutting-edge diagnostic capabilities and treatment options for companion animals with cancer.

2013 — The Lyons’ Feline Genetics Laboratory was established. It focuses on the genetics of the domestic cat, the development of genetic tools and resources that assist gene mapping in the cat and other companion animals, the discovery of mutations that cause inherited diseases and phenotypic traits, and population dynamics of breed development and domestic cat evolution.

2014 — The MU Metagenomics Center was established.  This center serves as a provider of next-generation sequencing services for users of research animal models and veterinary clinicians, and a database and repository for the archiving of metagenomics data and fecal samples respectively.

2014 — The MU Veterinary Medical Teaching Hospital acquired a new 3T Magnetic Resonance Imaging machine, adding to its research and diagnostic imaging capabilities that include positron emission tomography (PET), computed tomography (CT), and superior digital radiography. MU is one of only a few veterinary schools in the country with such advanced technology available.

Four CVM alumni have served as American Veterinary Medical Association presidents.

Through the efforts of Dr. Gary Johnson, the college has amassed clinical records and samples from 100,000 animals representing hundreds of breeds and dozens of inherited diseases.